hrp0086p2-p953 | Thyroid P2 | ESPE2016

Clinical Value of Thyroid-Stimulating Immunoglobulin in Paediatric Autoimmune Thyroid Diseases

Stozek Karolina , Bossowski Artur , Ziora Katarzyna , Bossowska Anna , Diana Tanja , Kahaly George J

Background: In Autoimmune Thyroid Disease (AITD) two types of TSH receptor antibodies (TSHR-Ab) may be distinguished: thyroid- stimulating immunoglobulin (TSI) that promotes the production of thyroid hormones and thyroid- blocking immunoglobulin (TBI) inhibiting the activity of TSH what leads contrarily to hypothyroidism.Objective and hypotheses: The aim of this study was to compare mean TSI and TBI levels in large paediatric cohort with AITD and control...